Open Studies

The Gut-Pro Study

What is the Gut-Pro Study?

The gut microbiome is the home for the many diverse microorganisms that support positive and negative health outcomes in humans. The gut is constantly changing, with research showing many lifestyle factors contributing to changes in the microbiome population. Certain species have been associated with Alzheimer ’s disease populations. This new study will test the ability of using probiotics to support the microbiome in individuals with or at risk of Alzheimer ’s disease.

What will I be asked to do?

  • Take probiotic supplements or placebo
  • Complete questionnaires
  • Complete blood draw
  • Undergo cognitive testing
  • Undergo physical exams
  • Provide stool samples

Who can volunteer?

  • At least 60 years old
  • Cognitively healthy, MCI, or early AD dementia
  • Can complete a phone AND in-person screening process with cognitive testing
  • Has a study partner available for questionnaires

Will I be paid?

Participants will be given up to $660 for completing all procedures.

Interest Survey:  https://tinyurl.com/gutprostudy

MRI of Brain Waste Clearance Study

Purpose

The purpose of this study is to collect brain scans and blood samples that will provide information about the brain’s waste clearance system. Researchers will evaluate applications of this knowledge to neurodegenerative diseases such as Alzheimer’s Disease and Parkinson’s Disease.

Who can participate?

  • At least 55 years old
  • Memory complaints for more than 6 months, diagnosis of mild cognitive impairment, or early AD dementia
  • Able to participate in an evening MRI scan

What will happen in this study?

This study consists of two in person visits to the Waisman Center within one month. One visit will include a blood draw, answering questionnaires, and a cognitive testing session. The other visit will be an evening MRI scanning session. Participants will be asked to keep a sleep diary and wear a wrist-based sleep monitoring device for seven days prior to the MRI scan.

Procedures during both visits:

Visit 1

Home

 Visit 2

  • Blood draw
  • Cognitive testing
  • Vital sign collection
  • Questionnaire administration

 

  • At home sleep diary entry and sleep monitoring via wrist-based device

 

 

 

  • MRI scan

 

 

 

 

Will I be paid during this study?

  • $30 for blood sample
  • $30 for cognitive testing and questionnaires
  • $30 for 7 day at home sleep diary entry and monitoring
  • $150 for evening MRI scanner session
  • Maximum payment is $240

Interested? Contact us or click here to access a participation survey!

E-mail*: brainsleep@waisman.wisc.edu

Phone: (608) 516-3232

*E-mail is not a secure form of communication. You should avoid sending sensitive personal information via email.