Our lab studies aging and Alzheimer’s disease.
We are interested in understanding the interplay of factors that contribute to healthy or pathological brain aging. In particular, the effect of factors that contribute to or protect against the development of Alzheimer’s disease.
We use a number of tools in our research, including cognitive testing, MRI, PET, and CSF analysis, to determine how risk factors for Alzheimer’s affect the brain, particularly in mid-life.
Our NIA funded research program is focused on characterizing the early effects of Alzheimer’s disease on brain myelin and axons, in addition to determining the role of preclinical inflammation in cell and dendritic damage.
Together with collaborators both on and off of the UW campus, the lab is also studying the impact of modifiable factors that may affect trajectories of aging. These include the effect of mid-life metabolic disorders (obesity and insulin resistance), sleep, diet, and microbial influences.
Understanding early brain changes in people who may go on to develop cognitive decline is expected to lead to earlier diagnosis, prevention, and the development of new therapies for Alzheimer’s disease.
Dr. Barbara Bendlin’s Mendeley profile.
Bendlin Lab News
Kao Lee Yang pens opinion piece after being miscategorized as overrepresented in science as a Hmong-American
MPA/PhD student Kao Lee Yang was nominated for the HHMI Gilliam Fellowship for Advanced Study, but her nomination was rejected by HHMI because she didn’t fit into its racial/ethnic underrepresentation criteria. Read her story.November 12, 2021
Dr. Gilda Ennis publishes findings on insulin resistance, cognitive decline, and AD biomarkers in journal Alzheimer’s and Dementia
Dr. Gilda Ennis, an assistant scientist in the Bendlin Lab, had her manuscript titled “Insulin resistance is related to cognitive decline but not change in CSF biomarkers of Alzheimer’s disease in non-demented adults” accepted for …July 28, 2021
Former Bendlin Lab trainee Dr. Nick Vogt MD,PhD was selected as the 40th recipient of the Jerzy E. Rose Neuroscience Award for original and significant research in the neurosciences. Congratulations Dr. Vogt!June 14, 2021
A heartfelt congratulations to all of our graduating Bendlin lab students. Best of luck with your future endeavors, and thank you for your contributions to the lab over the years! Graduate Students: Nick Vogt MD,PhD …May 17, 2021
Dr. Gilda Ennis, an assistant scientist in the Bendlin Lab, had her manuscript titled “The relationship of glucose-stimulated insulin secretion to cerebral glucose metabolism and cognition in healthy middle-aged and older adults” accepted for publication …May 3, 2021
- More Bendlin Lab News posts