Our lab studies aging and Alzheimer’s disease.
We are interested in understanding the interplay of factors that contribute to healthy or pathological brain aging. In particular, the effect of factors that contribute to or protect against the development of Alzheimer’s disease.
We use a number of tools in our research, including cognitive testing, MRI, PET, and CSF analysis, to determine how risk factors for Alzheimer’s affect the brain, particularly in mid-life. Our NIA funded research program is focused on characterizing the early effects of Alzheimer’s disease on brain myelin and axons, in addition to determining the role of preclinical inflammation in cell and dendritic damage.
Together with collaborators both on and off of the UW campus, the lab is also studying the impact of modifiable factors that may affect trajectories of aging. These include the effect of mid-life metabolic disorders (obesity and insulin resistance), sleep, diet, and microbial influences.
Understanding early brain changes in people who may go on to develop cognitive decline is expected to lead to earlier diagnosis, prevention, and the development of new therapies for Alzheimer’s disease.
Dr. Barbara Bendlin’s Mendeley profile.
Bendlin Lab News
Assistant researcher Kao Lee Yang was awarded an academic professional development can’t to attend the Human Amyloid Imaging annual conference in January. Congratulations Kao Lee!December 17, 2019
Yuetiva Robles, a postdoc in the Bendlin Lab, was chosen for an interview by the American Society of Human Genetics in regards to her new article published in Science Translational Medicine this past August. Her …October 29, 2019
Bendlin lab graduate student Margo Heston won a poster award at the UW-Madison Pathology Research Day for her work relating Alzheimer’s pathology and the gut microbiome. Congrats Margo!!August 28, 2019
Several Bendlin lab members attended this year’s Alzheimer’s Association International Conference in Los Angeles from July 13 – July 18. We presented posters and attended days of talks in an effort keep up-to-date on the …July 31, 2019