Barbara Bendlin, PhD
Dr. Bendlin is an Associate Professor in the Department of Medicine, Division of Geriatrics. She received her PhD at the University of Arizona in Tucson, and completed postdoctoral training at the University of Wisconsin. She subsequently joined the faculty at UW-Madison in 2010. Dr. Bendlin's research is focused on understanding brain and cognitive changes in normal and pathologic aging. Her federally funded studies use novel brain imaging techniques combined with fluid biomarkers to detect early brain changes in Alzheimer's disease, and to understand mechanisms of disease related neural injury, as well as determine the effect of factors that may increase or decrease risk of dementia. Email: bbb@medicine.wisc.edu
SCIENTISTS
Nagesh Adluru, PhD
After graduating with a PhD in Computer Science with a focus on computer vision, robotics and machine learning, Nagesh switched his research focus to the exciting area of neuroimaging in 2009. Over the past 11 years, his research interests have been shaped and homed in for developing state-of-the-art image processing, statistical and machine and deep learning methods, to transform advanced multi-shell diffusion weighted MR imaging (ms-dMRI) data from neuro-scientific studies to biologically interpretable and clinically effective knowledge. Within Dr. Bendlin’s lab his focus has been to develop and apply advanced non-linear regression and network neuroscience methods to analyze ms-dMRI data from the LEAD, ADCP and DIAN studies. He works with various biophysical diffusion models (e.g. NODDI, DKI based WMTI) beyond the traditional diffusion tensor imaging (DTI) to study microstructural and neural network changes due to Alzheimer’s disease and related dementia (ADRD) and their risk factors. Email: adluru@medicine.wisc.edu
Gilda Ennis, PhD
Dr. Ennis received her PhD in Psychology at North Carolina State University and completed postdoctoral training in cognitive aging at the Georgia Institute of Technology. She is interested in the association of prediabetes and diabetes to cognitive aging, dementia, and biomarkers of Alzheimer’s disease and neurodegeneration. Email: geennis@medicine.wisc.edu
Yuetiva (Deming) Robles, PhD
Dr. Robles is an assistant scientist in the Division of Geriatrics and Gerontology and is interested in analyzing quantitative traits to help further understanding of complex disease. Currently her research integrates genomics, metabolomics, and bioinformatics methods to help determine the underlying biology impacting Alzheimer disease (AD). Dr. Robles (Deming) received her Bachelor’s degrees in Neuroscience and Molecular Biology from the University of Colorado in Boulder, and earned her PhD from Washington University in St Louis School of Medicine where she focused on genetic associations with AD biomarkers such as CSF amyloid and tau to help uncover biological pathways associated with AD pathology. Google Scholar Profile. Email: yrobles@wisc.edu
GRADUATE STUDENTS
Akshay Kohli
Akshay is a PhD student in the Neuroscience Training Program at UW. His current research utilizes high-contrast MRI scans in combination with biomarkers of Alzheimer's Disease to investigate changes in structural integrity of brain tissue throughout the progression of the disease. By employing these new scan techniques, he hopes to provide a robust method of detecting AD-related neurobiological changes, leading to earlier and more reliable diagnosis and treatment. Google Scholar Profile. Email: akohli2@wisc.edu
Kao Lee Yang
Kao Lee Yang is a Phd/MPA student in the Neuroscience and Public Policy (NPP) program at the University of Wisconsin-Madison. She received her undergraduate and master's training in psychology at the University of Wisconsin-Stout and Ball State University, respectively. Despite years of research, there is no known cause for sporadic Alzheimer's disease and no known cure. With a rapidly aging multicultural population in the United States, one of Kao Lee's goals is to contribute to knowledge that will uncover the cause(s) and/or underlying pathophysiological cascades of this disease. To this end, Kao Lee's work centers on improving characterization of brain changes in Alzheimer's disease in order identify factors that contribute to pathological brain aging. She hopes her work can support foundational frameworks for identifying potential windows for interventions (such as diet or exercise regimens) or therapeutics (such as novel treatment drugs). Moreover, Kao Lee is passionate about identifying new ways in which the scientific community can equitably engage members from historically underrepresented groups as STEM researchers, and as STEM research participants. Her training in policy will equip her with tools to advance scientific investigations into Alzheimer's disease, as well as address the manner in which research has been carried out. Email: klyang3@wisc.edu
Margo Heston
Margo Heston is a PhD student in the Cellular and Molecular Pathology program at the University of Wisconsin-Madison. Previously, she received her Bachelor’s degree in biomedical engineering at Johns Hopkins University, where she studied the effects of profound hearing loss in midlife. Margo’s work examines how gut microbial, metabolic and neighborhood contextual factors may exacerbate inflammation and drive AD pathology. As a future investigator, she aims uncover novel mechanisms of pathologic aging that will inform clinical interventions and public health policy that promotes health equality. Google Scholar Profile. Email: mheston@wisc.edu
Henry Stephenson
Henry is a PhD student in the Neuroscience Training Program at UW-Madison. Email: hstephenson2@wisc.edu
Research Staff
Nancy Davenport-Sis - Program Manager
Nancy Davenport-Sis is the Program Manager for the Bendlin Lab in the Wisconsin ADRC. She oversees all the research studies conducted in Dr. Bendlin’s Lab, including recruitment, retention, and day to day operations. She is also responsible for supervising the undergraduate research assistants and contributing to the WADRC as a whole. Email: njdavenp@wisc.edu
Mary-Elizabeth Pasquesi - Study Coordinator
Mary-Elizabeth is the study coordinator for the ADCP. In this role, she recruits participants as well as schedules and carries out participant visits (coordinating lab tests, brain imaging appointments, and neuropsychological exams). In addition, she manages the ADCP team of staff, graduate, and undergraduate students. Email: mpasquesi@wisc.edu
Theresa Kang - Senior Research Specialist
Theresa is the study coordinator for Dr. Bendlin's LEAD study, the goal of which is to understand the longitudinal trajectories of white matter degeneration in Alzheimer's disease. She also provide assistance to other ADRC projects as needed. Email: tjkang@medicine.wisc.edu
Rachel Aune - Research Specialist
Rachel is the study coordinator for Dr. Bendlin's microbiota studies, which analyze the relationship between GI bacteria and risk for dementia due to Alzheimer's disease. Rachel is currently coordinating the Ambition study, which aims to demonstrate the effects of fecal microbiota transplant intervention on the composition and function of the gut microbiota in humans with or at risk for dementia due to Alzheimer's disease. She also provide assistance to other ADRC projects as needed. Email: rkaune@medicine.wisc.edu
Undergraduate Students
Tristan Ryan
Tristan is an undergraduate research assistant in the Bendlin Lab. His responsibilities include data entry and assistance on multiple studies, as well as image quality checks on MRI’s. He also is involved in many administrative duties. Email: tmryan2@wisc.edu
Allison Randall
Allie is a new student in the Bendlin Lab, working on reviewing MRI scans to check their image quality, and entering data for LEAD and PREDICT studies. She is currently learning more about insulin resistance and its impact on the brain as well as tracking biomarker changes in the CSF. Email: amrandall2@wisc.edu
Julia Bink
Julia is an undergraduate research assistant in the Bendlin Lab. Her responsibilities include data entry and assistance on multiple studies, as well as image quality checks on MRI’s. She also is involved in many administrative duties. Email: jbink@wisc.edu
Kelly Hartnett
Kelly is an undergraduate research assistant at the Bendlin Lab. She assists in coordinating study visits and reviews MRI scans for image quality. Email: kmhartnett@wisc.edu
Hanna Noughani
Hanna is an undergraduate research assistant. Currently, she performs general lab work in the Bendlin Lab at the ADRC. Email: hnoughani@wisc.edu
Allison Forst
Allison is an undergraduate research assistant in the Bendlin Lab. Her responsibilities include data entry and assistance on multiple studies, as well as image quality checks on MRI’s. She also is involved in many administrative duties. Email: aaforst@wisc.edu
Emily Merkel
Emily is an undergraduate research assistant at the Bendlin Lab. She assists in coordinating study visits and reviews MRI scans for image quality. Email: emerkel@wisc.edu
Jordan Doucette
Jordan is an undergraduate research assistant at the Bendlin Lab. He assists in coordinating study visits and reviews MRI scans for image quality. Email: jjdoucette@wisc.edu
Grace Everitt
Grace is an undergraduate research assistant. Currently, she performs general lab work and data entry in the Bendlin Lab. Email: geveritt@wisc.edu
Lab Alumni
Ingrid Taylor, DPT
Ingrid was a student researcher working on the AMBITION study while pursuing her Doctorate of Physical Therapy. Previously Ingrid was study staff and worked on ADCP screening participants, scheduling and running study visits. Now she works behind the scenes on AMBITION study procedures and administration. Email: itaylor3@wisc.eduEmail: itaylor3@wisc.edu
Nick Vogt, MD PhD
Nick Vogt was a student in the UW Medical Scientist Training Program. As a future physician-scientist and geriatrician, he is interested in providing clinical care to individuals suffering from Alzheimer’s disease and other dementias, while also investigating the factors that contribute to healthy or pathological brain aging. His thesis work focused on the role of human gut bacteria (or the "gut microbiome") in the development and progression of Alzheimer’s disease, as well as cortical microstructure alterations using NODDI imaging. He hopes that gaining a better understanding of the complex relationship between gut microbiota and Alzheimer’s disease will lead to novel interventions aimed at augmenting or restoring gut bacterial composition. Google Scholar Profile. Email: nvogt@wisc.edu
Maiya Macalpine
Maiya's responsibilities as a student researcher included conducting quality checks on MRI scans and entering data for LEAD and ADCP. She worked closely with the ADCP study coordinators to schedule participant visits, prepare lab kits, and carry out various administrative duties. Maiya also investigated the relationship between metabolic factors and hippocampal volume with the BFIT study. Maiya is now an IRTA fellow in the lab of Susan Resnick at the NIH. Email: macalpine@wisc.edu
Lily Allison
Lily was a research intern in the Bendlin lab. Her responsibilities included assisting with data entry and quality checks for ADCP. Lily also helped with participant recruitment and other various tasks needed for this study. Lily is now in medical school. Email: lallison2@wisc.edu
Morgen Spees
Morgen worked as a study assistant for the Alzheimer's Disease Connectome Project (ADCP). Her responsibilities included recruitment of participants as well as data entry, scheduling, and coordination of participant visits.
Michael Kozuch
Michael coordinated the activities of two studies: (1) a new, intervention-based study (BFIT) examining changes in brain blood flow, cognition, and other health metrics as they relate to a combined diet and exercise program, and (2) a longitudinal study (LEAD) of brain changes that might be related to developing Alzheimer’s Disease. Michael is now pursuing his masters in public health at Emory University.
Brittany Moreno
Brittany was a study coordinator for the Alzheimer Disease Connectome Project. She led research visits: cognitive and psychological assessments, MRI and PET imaging, and coordinated lab tests. Additional duties included subject recruitment, quality assessment, and scheduling. Brittany is now pursuing her doctorate in physical therapy at UW-La Crosse
Andrew Merluzzi, PhD
Andrew was a PhD/MPA Candidate in the Neuroscience and Public Policy (NPP) Program. He was seeking to chart cognitive decline in individuals at risk for Alzheimer’s disease and investigating biomarkers for resilience to dementia. His most recent findings showed that some middle-aged individuals have brains that look as if they should have dementia, but show no signs of cognitive impairment. That is, they have the characteristic misfolded proteins of Alzheimer’s (amyloid and tau) and yet were diagnosed as clinically unimpaired. His work has shown that these “resilient” individuals seem to have more stable connectivity between brain regions, stronger neuronal synapses, and reduced gliosis, perhaps allowing them to cope with increasing levels of amyloid and tau. Ultimately, this may suggest that additional biological processes will be useful predictors of who will go on to develop dementia or how we might prevent it. In addition to this project, Andrew also used novel diffusion-weighted and myelin imaging to detect brain changes early on in the Alzheimer's disease progression.
After graduating from the Neuroscience and Public Policy program, Andrew accepted a science and technology policy position at the Potomac Institute for Policy Studies. Google Scholar Profile. Email: andrewmerluzzi@gmail.com.
Nick VanDerwerker
Nick was an undergraduate research assistant at the ADRC. He reviewed and processed MRI scans to ensure that they are usable for research, and created post-visit results letters for research participants. Email: vanderwerker@wisc.edu
Deepali Bhalla
Deepali was an undergraduate research assistant at the ADRC. She reviewed and processed MRI scans to ensure that they are usable for research. Deepali conducted a research project looking at quantitative T1 in the Alzheimer's brain. Deepali continued on to medical school at Medical College of Wisconsin. Email: dmbhalla@wisc.edu
Jack Hunt, MD PhD
Jack was a student in the UW Medical Scientist Training Program and the Program in Cellular and Molecular Biology. He has clinical interest in the care of patients with neuropsychiatric disorders and a passion for research in the neurobiology underlying these conditions. His research in Dr. Bendlin's Lab used state of the art PET and MRI imaging techniques to identify how early Alzheimer's disease pathology spreads throughout the human brain. His work sought to uncover how the accumulation of the toxic Alzheimer's disease protein, tau, relates to white matter pathology in the brain. The goal of the work was to provide new insights into early brain changes in Alzheimer's disease and to uncover biomarkers to track the efficacy of new treatments and interventions. Google Scholar Profile. Email: jfhunt2@wisc.edu
Grace Mckinney
Grace was a study coordinator for the Synapse Project. In this role, she recruited participants as well as scheduled and carried out participant visits (lab tests and brain imaging appointments). Email: gmckinney@medicine.wisc.edu
Rigina Gallagher, MA
Rigina is a student in the UW Medical Scientist Training Program and the Neuroscience Training Program. Rigina completed her thesis work in the Bendlin lab and is currently finishing medical school as part of the MSTP. Email: rgallagher2@wisc.edu
Leah Mushall
Leah was an undergraduate student researcher in the Bendlin lab. Her responsibilities included assisting with data entry and other tasks for LEAD, PAMMS and BFIT. Leah also worked on sending reminder and results letters for a few different studies. Email: mushall@wisc.edu
Chase Taylor
Chase coordinated our studies on insulin resistance, sleep apnea, and risk for Alzheimer's disease. In addition, he also provided assistance on other ADRC projects as needed, including on the LEAD project (otherwise known as: "White matter degeneration: biomarkers in preclinical Alzheimer's disease"). Chase is now pursuing his doctorate in Neuroscience at the University of Kentucky. Email: ctaylor23@uky.edu
Alex Jankovich
Alex was an undergraduate student researcher in Dr. Bendlin’s lab. His responsibilities included assisting with data entry and other tasks for LEAD, PAMMS, and BFIT. Alex also worked closely with MARS study coordinators to schedule participant visits, prepare lab kits, and carry out various administrative duties. He has previously studied the relationship between central obesity and beta-amyloid accumulation with PAMMS.
Matthew Beilfuss
Matt was an undergraduate student researcher in Dr. Bendlin's lab. His responsibilities included assisting with data entry and other tasks for the LEAD, PAMMS, PREDICT, and ADNI studies. Matt also trained new undergraduate students and had previously coordinated the LEAD study. He investigated the relationship between the human gut microbiome and Alzheimer's disease as an undergraduate research assistant for the MARS study. He is currently in medical school at UW-Madison. Email: mabeilfuss@wisc.edu
Bobbi Audrey
Bobbi was an undergraduate student researcher in the Bendlin lab. Her primary responsibilities were quality checking MRI's (e.g. checking for motion artifacts and signal dropout) as well as orientating them for analysis (ACPC correction). Bobbi also performed data entry following participant visits for many studies in the lab, including cognitive data and health history data. Email: baubrey@wisc.edu
Erika Starks, MD, PhD
Erika was a student within the Medical Scientist Training Program and Neuroscience Training Program at UW. She is now a radiology resident at the University of New Mexico.
Siobhan Hoscheidt, PhD
Siobhan was a postdoctoral researcher in the Bendlin Lab. She is now an assistant professor of gerontology and geriatric medicine at Wake Forest University.
John Thorstenson
John was an undergraduate research assistant in the Bendlin Lab, and his responsibilities included data entry for multiple studies, such as PREDICT, LEAD, PAMMS, ADCP, and MARS, and doing image quality checks and AC/PC corrections on MRI scans. He was closely involved with MARS, the gut microbiome study, performing phone screenings and sample kit preparations. Email: jthorstenson@wisc.edu
Ana Hoeft
Ana was an undergraduate research assistant in the Bendlin Lab. Her responsibilities included data entry and assistance on multiple studies such as BFIT and PAMMS, as well as image quality checks and ACPC correction on MRI’s. She also was involved in many administrative duties. Email: ahoeft2@wisc.edu
Sarah Brooks
Sarah was an undergraduate research assistant in the Bendlin Lab, and her responsibilities included data entry and conducting MRI quality checks for the ADCP study. She studied the effects of mild cognitive impairment and Alzheimer’s disease on episodic memory in older adults with the ADCP study. Email: sebrooks@wisc.edu
Jessi Kelley
Jessi was an undergraduate student researcher involved with several studies, including PAMMS, LEAD, BFIT, ADNI, and PREDICT. She conducted image quality checks and data entry, and also assisted with the training of new students. With respect to research, Jessi investigated the relationship between myelin and Alzheimer’s biomarkers in cerebrospinal fluid.
Jonilda Mecollari
Jona was an undergraduate student researcher in the Bendlin lab, and focused on data entry, scheduling, and recruiting for ADCP. Her other duties included image quality checks, ACPC corrections, and other tasks for additional studies such as LEAD and PAMMS. She loved training new students, assisting with technical designs in projects, and interacting with research participants.
Kevin Jones
Kevin enjoyed working as an undergraduate student researcher in the Bendlin Lab. His primary responsibilities were quality checking MRI scans and entering data from LEAD and PREDICT research visits. Additionally, Kevin has worked with study coordinators on sending recruitment letters for new research studies.
Martina Ly, PhD
Martina was a student within the Neuroscience Training Program at UW. She is now a Technology and Business Development Consultant for ANT Neuro.
Auriel Willette, PhD
Auriel was a postdoctoral researcher in the Bendlin Lab. He is now an assistant professor within the departments of Food Science and Human Nutrition and Psychology at Iowa State University.
Kate Sprecher, PhD
Kate graduated with her PhD through the Neuroscience Training Program at UW. She is now a postdoctoral researcher in the Sleep and Chronobiology Lab at University of Colorado Boulder.
Brittany Derynda
Brittany was an undergraduate student researcher in the Bendlin Lab, and her responsibilities included assisting with data entry, preparing for research visits, and training new undergraduate students. Brittany also provided assistance on the BFIT study, which she previously coordinated, and the PAMMS study. Additionally, she investigated the relationship between sleep-disordered breathing and brain white matter health.